Zach Cregger's new Resident Evil film has earned approximately $250 million worldwide, placing it third among all Resident Evil movies at the box office. The film received solid critical reviews and strong audience reception.

Paul W.S. Anderson's 2016 film "The Final Chapter" holds the top spot for highest-grossing Resident Evil movie. Anderson directed six Resident Evil films starring his wife Milla Jovovich before Cregger's entry into the franchise. While critics did not receive Anderson's films well, they maintained a dedicated fanbase that consistently attended screenings. His six movies generated more than $1 billion combined at the box office.

Cregger's film ranks just behind the top two highest-grossing entries in the franchise. The movie would need to earn significantly more to surpass "The Final Chapter" for the number one position. The Resident Evil film franchise has demonstrated consistent commercial appeal despite mixed critical reception for earlier installments.